PT  - JOURNAL ARTICLE
AU  - Ran D. Goldman
TI  - Acetaminophen in children
DP  - 2013 Oct 01
TA  - Canadian Family Physician
PG  - 1065--1066
VI  - 59
IP  - 10
4099  - http://www.cfp.ca/content/59/10/1065.short
4100  - http://www.cfp.ca/content/59/10/1065.full
SO  - Can Fam Physician2013 Oct 01; 59
AB  - Question I frequently suggest to parents to use acetaminophen to treat their children’s fever and pain. Recently, I had a child in my office who presented with a target-lesion skin rash a day after receiving acetaminophen. The rash resolved after 3 days and after stopping administration of acetaminophen. Does acetaminophen carry a risk of adverse events such as this? Answer Like any other medication or active substance, acetaminophen preparations might carry a risk of adverse events. In recent years a potential association between acetaminophen and asthma was investigated, and the US Food and Drug Administration recently published a warning about potential severe but rare skin reactions associated with acetaminophen. Although acetaminophen is mostly a safe medication, health care providers should be alert and advise parents about the possibility of rare but severe adverse events.