TY - JOUR T1 - Botulinum toxin type A in pregnancy JF - Canadian Family Physician JO - Can Fam Physician SP - 1183 LP - 1184 VL - 59 IS - 11 AU - Michael Tan AU - Eunji Kim AU - Gideon Koren AU - Pina Bozzo Y1 - 2013/11/01 UR - http://www.cfp.ca/content/59/11/1183.abstract N2 - Question My patient received 62 units of botulinum toxin type A (BTX-A) for facial lines. Two weeks later, she found out that she was pregnant. Will this cause any harm to her fetus? Answer Botulinum toxin is not expected to be present in systemic circulation following proper intramuscular or intradermal injection. Moreover, BTX-A, which has a high molecular weight, does not appear to cross the placenta. From the 38 pregnancies reported in the literature, including women who had botulism poisoning during pregnancy, exposure to BTX-A does not appear to increase the risk of adverse outcome in the fetus. ER -