PT  - JOURNAL ARTICLE
AU  - Michelle Sherwood
AU  - Ran D. Goldman
TI  - Effectiveness of riboflavin in pediatric migraine prevention
DP  - 2014 Mar 01
TA  - Canadian Family Physician
PG  - 244--246
VI  - 60
IP  - 3
4099  - http://www.cfp.ca/content/60/3/244.short
4100  - http://www.cfp.ca/content/60/3/244.full
SO  - Can Fam Physician2014 Mar 01; 60
AB  - Question The rate of migraine diagnosed among children is increasing. Is riboflavin, an alternative to traditional pharmacologic agents, effective and safe for prevention of migraine in children? Answer Because migraine is a very common condition in childhood and adolescence, often contributing to substantial burden of illness, there is increased interest in alternatives to traditional pharmacologic prevention. The expectation is that over-the-counter alternative medication will be less toxic, better tolerated, and have fewer side effects. A few studies in adults show that riboflavin (vitamin B2) might decrease frequency of migraine headaches. It has become common practice to recommend that children try riboflavin to prevent migraine; however, research on riboflavin use in children is inconclusive.