@article {Gesinke96, author = {Dionne Gesink and C. Sarai Racey and Christine Seah and Sandra Zittermann and Leo Mitterni and Jerry Juzkiw and Heather Jamieson and Jane Greer and Sudesh Singh and J{\o}rgen Skov Jensen and Vanessa Allen}, title = {Mycoplasma genitalium in Toronto, Ont}, volume = {62}, number = {2}, pages = {e96--e101}, year = {2016}, publisher = {The College of Family Physicians of Canada}, abstract = {Objective To estimate the prevalence of Mycoplasma genitalium in Toronto, Ont; detect mutations associated with macrolide and fluoroquinolone resistance; and describe treatment outcomes.Design Prospective, cross-sectional study.Setting A sexual health clinic in Toronto.Participants A consecutive sample of men and women attending the sexual health clinic between September 1, 2013, and December 20, 2013.Interventions Participants underwent testing for M genitalium, along with standard sexually transmitted infection screening. All samples that had positive results for M genitalium were tested for mutations associated with resistance to macrolides and fluoroquinolones. Mycoplasma genitalium treatment was based on resistance profile and verified with a test of cure.Main outcome measures Positive results for M genitalium and antibiotic resistance.Results A total of 1193 men and women participated in the study. Overall, 4.5\% of the 884 men and 3.2\% of the 309 women had positive test results for M genitalium. Asymptomatic infection was common (52.0\%). Macrolide resistance{\textendash}mediating mutations were found in 58.0\% of the M genitalium infections. No treatment failure was observed for azithromycin-treated cases. Treatment failure was suspected for 16.7\% of cases treated with moxifloxacin.Conclusion Mycoplasma genitalium is present in Canada, with a prevalence comparable to chlamydia and gonorrhea, and has high macrolide and fluoroquinolone resistance.}, issn = {0008-350X}, URL = {https://www.cfp.ca/content/62/2/e96}, eprint = {https://www.cfp.ca/content/62/2/e96.full.pdf}, journal = {Canadian Family Physician} }