PT  - JOURNAL ARTICLE
AU  - Ran D. Goldman
TI  - Acyclovir for herpetic gingivostomatitis in children
DP  - 2016 May 01
TA  - Canadian Family Physician
PG  - 403--404
VI  - 62
IP  - 5
4099  - http://www.cfp.ca/content/62/5/403.short
4100  - http://www.cfp.ca/content/62/5/403.full
SO  - Can Fam Physician2016 May 01; 62
AB  - Question Every year I see preschool children with gingivostomatitis. There seems to be quite a substantial burden of illness with this condition. Because it is caused by herpes simplex virus type 1, should I prescribe antiherpetic therapy with oral acyclovir?Answer While most children with primary gingivostomatitis will be asymptomatic, some will experience considerable pain and discomfort and are at risk of dehydration. There are no large, well designed studies to clearly determine appropriate therapy for all children. Based on a single randomized study, treatment should be started only within the first 72 hours of symptom onset if substantial pain or dehydration are documented.