RT Journal Article
SR Electronic
T1 Intranasal midazolam for seizure cessation in the community setting
JF Canadian Family Physician
JO Can Fam Physician
FD The College of Family Physicians of Canada
SP 559
OP 561
VO 62
IS 7
A1 Michal Zelcer
A1 Ran D. Goldman
YR 2016
UL http://www.cfp.ca/content/62/7/559.abstract
AB Question There are times when parents arrive to my clinic after their child has had a seizure and a second seizure takes place in the clinic. While waiting for transport to the hospital, are there ways to stop the seizures without the need to obtain intravenous access in the clinic?Answer Intravenous diazepam has been a first-line therapy to stop seizures in children for many years. Other routes of drug administration such as intramuscular, rectal, and buccal are available but have several limitations. More evidence suggests that the intranasal route to administer drugs is quick and effective in children, and the use of midazolam has been continuing to show promise in seizure cessation. With its good safety profile, intranasal midazolam can be used in the clinic and prehospital setting for seizure cessation in children.