Potential causes of chest pain
| CARDIAC CAUSES |
| Atherosclerotic coronary artery disease |
| Congenital coronary artery disease |
| Coronary spasm |
| Systemic hypertension |
| Pulmonary hypertension |
| Aortic stenosis |
| Aortic insufficiency |
| Hypertrophic cardiomyopathy |
| Severe anemia |
| Severe hypoxia |
| Polycythemia |
| Aortic dissection |
| Aortic aneurysm |
| Pericarditis |
| Mitral valve prolapse |
| Myocarditis |
| Cardiomyopathy |
| GASTROINTESTINAL CAUSES |
| Nutcracker esophagus |
| Diffuse esophageal spasm |
| Nonspecific motility disorder |
| Achalasia |
| Gastroesophageal reflux |
| Mallory-Weiss syndrome |
| Esophagitis |
| Candida infection |
| Herpes |
| Irradiation-induced pain |
| Esophageal foreign body |
| Peptic ulcer disease |
| Pancreatitis |
| Biliary disease |
| Splenic infarction |
| Gaseous bowel distention |
| NEUROMUSCULOSKELETAL CAUSES |
| Thoracic outlet syndrome |
| Anterior scalenus hypertrophy |
| Cervical rib syndrome |
| Cervical disc disease |
| Costochondritis or Tietze’s syndrome |
| Chest wall trauma or rib fracture |
| Malignancy |
| Herpes zoster |
| Precordial catch syndrome |
| Entrapment of nerves by sternal wire sutures |
| Xiphodynia |
| Slipping rib syndrome |
| Ostealgia due to neoplasm |
| Intercostal neuritis |
| Costovertebral joint dysfunction |
| PULMONARY CAUSES |
| Pulmonary embolism |
| Pneumothorax |
| Pneumonia |
| Pleuritis |
| Bronchospasm |
| Pulmonary hypertension |
| Tracheitis or tracheobronchitis |
| Intrathoracic tumour |
| PSYCHIATRIC CAUSES |
| Depression |
| Anxiety |
| Panic attacks |
| Malingering |
| OTHER CAUSES |
| Cocaine use |
| Lymphoma |
| Diabetes |
| Uremia |
| Renal stones |
| Mondor’s syndrome |
| Mediastinitis |
| Mediastinal emphysema |
| Mediastinal neoplasm |