Table 1

Factors that suggest biochemical recurrence (BCR) represents local vs distant disease after primary treatment with surgery or radiotherapy

Initial pathologyGleason score < 7Gleason score ≥ 7
Positive surgical marginExtra-prostatic involvement
No nodal involvementNodal involvement
Time to BCR after treatment> 1–2 y< 1 y
Pretreatment PSA level< 10 ng/mL> 10 ng/mL
PSADT> 12 mo< 6–12 mo
  • PSA—prostate-specific antigen, PSADT— prostate-specific antigen doubling time.