5-HT RECEPTOR | MAIN ACT ION RELATED TO SEROTONIN TOXICITY |
---|---|
5-HT1A | Neuronal inhibition, regulation of sleep, feeding, thermoregulation, hyperactivity associated with anxiety, hypoactivity associated with depression |
5-HT1D | Locomotion, muscle tone |
5-HT2A | Neuronal excitation, learning, peripheral vasoconstriction, platelet aggregation |
5-HT2B | Stomach contraction |
5-HT3 | Nausea and vomiting, anxiety |
5-HT4 | Gastrointestinal motility |
5-HT—serotonin.
Data from Boyer and Shannon.4