Lymph nodes | Pain and swelling in axillary, supraclavicular, or infraclavicular areas | Axillary, supraclavicular, or infraclavicular adenopathy |
Bone | Pain in bones out of keeping with patients’ usual pain, without previous trauma and not responding to medication | Tenderness on percussion of the spine |
Liver | Abdominal pain, early satiety | Enlarged liver on palpation, with a firm liver edge |
Lung | Shortness of breath | Auscultation and percussion of lungs compatible with pleural effusion or pulmonary edema |
Brain | Morning headache, vomiting | Neurologic symptoms, papilledema |