Table 5

Knowledge of hereditary breast, ovarian, and colorectal cancers: Respondents’ answers to multiple-choice questions, baseline questionnaire (Q1) versus follow-up questionnaire (Q3).

QUESTIONS*Q1 N = 21 N (%)Q3 N = 20 N (%)P VALUE (MCNEMAR TEST)
“Suppose you had a patient whose aunt or grandmother on her father’s side carries the BRCA1 gene mutation for breast/ ovarian cancer syndrome. In your opinion, could your patient also be a carrier of this mutation?”
  •Yes 15 (71)(90) 18.219
  •No2 (10)1 (5)
  •Not sure4 (19)1 (5)
“In your opinion, what percentage of female breast cancer patients has a BRCA1 or BRCA2 gene mutation?”
  •< 100%19 (90)18 (90)> .99
  •> 10%–100%01 (5)
  •Not sure2 (10)1 (5)
“In your opinion, what percentage of patients who carry a gene for hereditary non-polyposis colorectal cancer will actually go on to develop colorectal cancer?”
  •< 50%9 (43)7 (35).031§
  •≥ 50%5 (24)10 (50)
  •Not sure7 (33)3 (15)
  • * Questions are from Wideroff et al.29

  • One participant did not answer this question.

  • Correct answer.

  • § Significant difference between correct and incorrect answers.