Table 1.

Number of adverse drug events associated with hospitalizations among older adult inpatients (≥ 65 years) between 2006 and 2008: N = 92 141.

DRUG CLASSNO. OF ADVERSE DRUG EVENTS ASSOCIATED WITH HOSPITALIZATIONS, %*
Anticoagulants14 223 (15.4)
Antineoplastic agents9762 (10.6)
Opioids8458 (9.2)
All anti-infective agents7215 (7.8)
All diuretics6182 (6.7)
NSAIDs (including salicylates)6030 (6.5)
Cardiac stimulant glycosides3982 (4.3)
Glucocorticoids3624 (3.9)
β-Blockers3526 (3.8)
Angiotensin-converting enzyme inhibitors2004 (2.2)
Antipsychotics and neuroleptics1713 (1.9)
Calcium channel blockers1643 (1.8)
Insulin and oral hypoglycemic agents1551 (1.7)
Other antidysrhythmic drugs not otherwise classified1488 (1.6)
Benzodiazepines, other sedatives, and anti-anxiety medications1441 (1.6)
Antidepressants1199 (1.3)
X-ray contrast media1038 (1.1)
  • NSAIDs—nonsteroidal anti-inflammatory drugs.

  • * Small cells are suppressed. Total does not add to 100%.