Serologic tests for celiac disease
| ANTIGEN | ANTIBODY TYPE | TEST | SENSITIVITY, % (RANGE) | SPECIFICITY, % (RANGE) |
|---|---|---|---|---|
| Gliadin | IgA | ELISA | 85 (57–100) | 90 (47–94) |
| IgG | ELISA | 80 (42–100) | 80 (50–94) | |
| Endomysium | IgA | IFA | 95 (86–100) | 99 (97–100) |
| IgG | IFA | 80 (70–90) | 97 (95–100) | |
| Tissue transglutaminase | IgA | ELISA | 98 (78–100) | 98 (90–100) |
| IgG | ELISA | 70 (45–95) | 95 (94–100) | |
| Deamidated gliadin peptide | IgA | ELISA | 88 (74–100) | 90 (80–95) |
| IgG | ELISA | 80 (70–95) | 98 (95–100) |
ELISA—enzyme-linked immunosorbent assay, IgA—immunoglobulin A, IgG—immunoglobulin G, IFA—immunofluorescence assay.
Data from Leffler and Schuppan.15