Determination of “nonswitching” constant: The nonswitching constant was the proportion of patients who, when prescribed their first medication, were not likely to change to another intraclass medication.
| CLASS | AVERAGE TOLERABILITY, % | TOLERABILITY FOR LEAST EXPENSIVE MEDICATION IN CLASS, % | CHOSEN NONSWITCHING CONSTANT |
|---|---|---|---|
| Statins | 94.443 | 97.543 | 94 |
Proton pump inhibitor | 80–9544 | 85–9545 8744 | 80 |
| Angiotensin-converting enzyme inhibitors | 9233 | 9546 | 92 |
Selective serotonin reuptake inhibitors | 60–6547 9747 | 60–65 | 60 |