Table 2.

Medications for COPD currently available in Canada

MEDICATIONDEVICEUSUAL DOSE
SABAs
  • SalbutamolMetered-dose inhaler1–2 puffs inhaled 4 times daily as needed
Diskus1 puff inhaled 4 times daily as needed
Nebule2.5 mg inhaled 4 times daily as needed
  • TerbutalineTurbuhaler1 puff inhaled 4 times daily as needed
SAMA
  • IpratropiumMetered-dose inhaler2 puffs inhaled 4 times daily as needed
Nebule500 µg inhaled 4 times daily as needed
Combination SABA and SAMA
  • Salbutamol and ipratropiumNebule1 ampoule inhaled 4 times daily as needed
Respimat1 puff inhaled 4 times daily as needed
LAMAs
  • TiotropiumHandiHaler1 capsule inhaled once daily
Respimat2 puffs inhaled once daily
  • AclidiniumGenuair1 puff inhaled twice daily
  • GlycopyrroniumBreezhaler1 capsule inhaled once daily
  • UmeclidiniumEllipta1 puff inhaled once daily
LABAs
  • SalmeterolDiskus1 puff inhaled twice daily
  • FormoterolAerolizer1 capsule inhaled twice daily
Turbuhaler6–12 µg inhaled twice daily
  • IndacaterolBreezhaler1 capsule inhaled once daily
  • OlodaterolRespimat2 puffs inhaled once daily
Combination LAMA and LABA
  • Umeclidinium and vilanterolEllipta1 puff inhaled once daily
  • Glycopyrronium and indacaterolBreezhaler1 puff inhaled once daily
  • Tiotropium and olodaterolRespimat2 puffs inhaled once daily
  • Aclidinium and formoterolGenuair1 puff inhaled twice daily
Combination LABA and ICS
  • Formoterol and budesonideTurbuhaler12 µg and 400 µg inhaled twice daily
  • Salmeterol and fluticasoneDiskus50 µg and 250 µg inhaled twice daily
  • Vilanterol and fluticasoneEllipta1 puff inhaled once daily
  • COPD—chronic obstructive pulmonary disease, ICS—inhaled corticosteroid, LABA—long-acting β-agonist, LAMA—long-acting muscarinic antagonist, SABA—short-acting β-agonist, SAMA—short-acting muscarinic antagonist.