The PPV of the first urine ACR to diagnose microalbuminuria, based on urine ACR range
| FIRST URINE ACR RANGE, mg/mmol | TRUE POSITIVE,* N | FALSE POSITIVE,† N | PPV (95% CI), % | EXCLUSIONS,‡ N |
|---|---|---|---|---|
| ≥2 to < 4 | 223 | 11 | 95.3 (92.6–98.0) | 314 |
| ≥4 to < 6 | 114 | 3 | 97.4 (94.6–100.3) | 78 |
| ≥6 to < 8 | 73 | 1 | 98.6 (96.0–101.3) | 22 |
| ≥8 to < 10 | 42 | 2 | 95.5 (89.3–101.6) | 13 |
| ≥10 to < 12 | 36 | 1 | 97.3 (92.1–102.5) | 7 |
| ≥12 to < 14 | 29 | 1 | 96.7 (90.2–103.1) | 6 |
| ≥14 to < 16 | 25 | 0 | 100.0 (100.0–100.0) | 2 |
| ≥16 to < 18 | 18 | 0 | 100.0 (100.0–100.0) | 1 |
| ≥18 to ≤ 20 | 13 | 0 | 100.0 (100.0–100.0) | 2 |
| ≥2 to ≤ 20 | 573 | 19 | 96.80 (95.37–98.21) | 445 |
ACR—albumin-to-creatinine ratio, PPV—positive predictive value.
↵* True positive: a positive urine ACR result was followed by another positive urine ACR result or by 1 negative and 1 positive urine ACR result in 120 days.
↵† False positive: a positive urine ACR result was followed by 2 negative urine ACR results in 120 days.
↵‡ Exclusions: a positive urine ACR result was followed by a negative urine ACR result but a third value was not available.