Aspects of the absorption of oral L-thyroxine in normal man☆
References (18)
- et al.
Absorption of thyroxine from the intestine of rats
Am J Physiol
(1967) - et al.
Treatment of hypothyroidism: A reappraisal of thyroxine therapy
Br Med J
(1973) Absorption of oral thyroxine in man
J Clin Endocrinol
(1968)Absorption of triiodothyronine in man
J Clin Endocrinol
(1970)Autoregulation of thyroxine secretion into bile
J Physiol
(1972)Qualitative and quantitative aspects of thyroxine metabolism
Endocrinology
(1969)Concentration of thyroxine in cellular and extracellular tissues of the sheep and the rate of equilibration of labelled thyroxine
Endocrinology
(1974)- et al.
Einfluss von D-Thyroxin auf das PB127J im Serum
Acta Endocrinol
(1969) - et al.
Thyroid suppression test with a single 3 mg dose of 1-thyroxine
Acta endocrinol
(1973)
Cited by (119)
Influence of Levothyroxine With Recombinant Human Thyroid-Stimulating Hormone on Urinary Iodine Excretion Before Radioactive Iodine Administration
2021, Endocrine PracticeCitation Excerpt :This levothyroxine-induced increase in the iodine pool can be calculated. Considering that the mean dose of levothyroxine in the rhTSH group was 115.2 μg/day, iodine accounts for 63.5% of the levothyroxine volume, and the absorption rate of ingested levothyroxine under fed conditions in euthyroid patients is greater than 60%,18 the 24UI value would be expected to be more than 43.5 μg/day higher in the rhTSH group than in the THW group, based on the assumption that oral intake and urinary excretion of iodine is in a steady state. However, the observed difference between the groups was 29.0 μg/day, which is consistent with the results of previous reports measuring UICR11 and urinary iodine concentration.10
Impact of Lifestyle Changes during Ramadan on Thyroid Function Tests in Hypothyroid Patients Taking Levothyroxine
2020, Endocrine PracticeCitation Excerpt :We hypothesize that the small male sample size limited the statistical power of this particular coefficient (males, n = 10). Based on the estimated 20% reduction in levothyroxine absorption (2,3) and approximately 3-fold increase in plasma TSH when levothyroxine was administered with food (6), we hypothesized that the post-Ramadan increase in plasma TSH in our study would be differentially related to changes in the eating habits during Ramadan leading to altered compliance with levothyroxine administration instructions. However, no evidence was found to support this hypothesis in the outcomes model, which relied on patient-reported levothyroxine use in relation to meals during Ramadan.
Discharged on Enteral Nutrition: What Now? The Poor State of Outpatient Support for Patients on Enteral Nutrition Support
2023, Current Gastroenterology ReportsImproper administration Silent culprit of drug therapy problems
2023, Canadian Family PhysicianImproper administration: Silent culprit of drug therapy problems
2023, Canadian Family Physician
- ☆
Supported in part by Deutsche Forschungsgemeinschaft (S1 95/3).