Effect of Momordica charantia on the glucose tolerance in maturity onset diabetes
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Cited by (191)
Plant Poisons, Hallucinogens, and Traditional Medicines
2023, Manson's Tropical Diseases, Fourth EditionMomordica charantia (bitter melon) modulates adipose tissue inflammasome gene expression and adipose-gut inflammatory cross talk in high-fat diet (HFD)-fed mice
2019, Journal of Nutritional BiochemistryCitation Excerpt :Several animal studies have demonstrated the antiobesity, antidiabetic, antioxidant and anti-inflammatory properties of BM regardless of different varieties of BM, differences in the levels of BM dosages, duration of treatment, animal models as well as the formulation of HFD diet [24,26–29,31,56–58,127,128]. Encouraging preclinical studies further corroborate antidiabetic properties of BM in humans [26,31,129–131]. Since inflammasomes are critical mediators of inflammation during obesity and insulin resistance [11,15,19], our study is the first to indicate that antiobesity and antidiabetic effects of freeze-dried BM juice may be associated with its capacity to inhibit mRNA expression of components of inflammasome, several NOD receptors and their downstream signaling targets.