Clinical InvestigationPrevention and RehabilitationExercise effects on lipids in persons with varying dietary patterns—does diet matter if they exercise? Responses in Studies of a Targeted Risk Reduction Intervention through Defined Exercise I
Section snippets
Subjects and experimental design
The STRRIDE I study design, hypotheses, recruitment strategies, methods, preliminary results, and the initial findings for exercise effects on serum lipids are published elsewhere.3, 4 Written informed consent was obtained from all subjects. In this analysis, we report on the 204 subjects for whom full nutrition and lipid information was available. There were no significant differences (P < .05 for all) in age, gender, race, or body mass index (BMI) between the subjects not included (n = 23)
Results
Median intakes of the target nutrients were similar to those reported in representative national studies (Table II). Intakes of fat and saturated fat tended to exceed, and intakes of omega-3 fatty acids and fiber fall to short of recommended standards. Diet patterns (diet z-scores) and reported calorie intakes (2009 [± 433], 2029 [± 481]), 2012 [± 497]), and 2119 [± 519] kcal for the control, L/M, L/V, and H/V groups, respectively) did not vary significantly between treatment groups (P = .61 and P
Discussion
As previously published from STRRIDE I findings, we observed that an aerobic exercise intervention, in the absence of clinically significant weight loss, improves lipoprotein profiles.4 Here, we extend these findings by reporting that exercise-mediated improvements in lipoprotein profiles are independent of the extent to which participants adhered to an AHA-recommended diet pattern. Our findings suggest that when an exercise regimen is instituted to improve lipoprotein profiles, at least within
Disclosures
None.
Acknowledgements
We would like to acknowledge the STRRIDE I participants and the rest of the STRRIDE research team at Duke University Medical Center and East Carolina University.
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Vera Bittner, MD, MSPH, served as guest editor for this article.