Inappropriate sexual behaviors in cognitively impaired older individuals
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Managing sexual behavior disorders in geriatric facilities
2023, NPG Neurologie - Psychiatrie - GeriatrieBehavioral and psychological symptoms in Alzheimer's dementia and vascular dementia
2019, Handbook of Clinical NeurologyCitation Excerpt :While there are no RCTs of pharmacologic agents in the treatment of ISBs, case reports and case series have demonstrated some success with antidepressants (e.g., trazodone, citalopram), ChEIs, cimetidine, hormonal agents (e.g., medroxyprogesterone or conjugated estrogen in males), and anticonvulsant medications (e.g., gabapentin, carbamazepine). Antidepressants may have the most evidence (albeit still limited), with the least risk of harm (Guay, 2008). One common source of anxiety among caregivers is the possibility of their loved one wandering and becoming lost.
Progestins used in endocrine therapy and the implications for the biosynthesis and metabolism of endogenous steroid hormones
2017, Molecular and Cellular EndocrinologyCitation Excerpt :Similarly, Dowsett and co-workers also reported decreased serum levels of A4 and testosterone in postmenopausal breast cancer patients after the administration of MPA, at both low (100 mg three times a day) and high (250 mg four times a day) doses (Dowsett et al., 1987). Total testosterone serum concentrations were also reduced in men administered 100–1000 mg MPA weekly for the treatment of abnormal sexual behavior (Guay, 2008). More recent studies, however, have also investigated the effects of progestins from later generations, including LNG, norgestimate, GES, NoMAC and DRSP.
Ageing and sexuality
2016, European Geriatric MedicineCitation Excerpt :Therefore, it is central to maintain discussions with family members and, when possible, with patients about the potential benefits and risks of treatment and to document these discussions [58]. For example, hormonal treatment is controversial because it may be viewed as a form of chemical castration [61]. Additionally, treatment for other behavioural symptoms that patients may be experiencing simultaneously seems suitable for the overall symptom complex [56].
Late-Onset Sex Offending and the Assessment of Behavioral Variant Frontotemporal Dementia (bvFTD)
2023, Journal of the American Academy of Psychiatry and the LawManaging the Behavioral and Psychological Symptoms of Dementia
2022, Current Treatment Options in Neurology