Case ReportGenital ulcers caused by Epstein-Barr virus☆
Section snippets
Case 1
A 19-year-old woman presented to the emergency department with a 1-week history of painful vulvar ulcers, dysuria, and fever. She had engaged in sexual contact with a new partner 6 weeks earlier. Oral acyclovir was empirically started. However, a herpes simplex virus (HSV) culture was negative. The ulcers persisted and increased in number. Three days later she was referred to the gynecology department. Again, an HSV culture was negative. The patient was then referred to the dermatology
Discussion
Determining the cause of vulvar ulcers can be challenging. The clinical presentation and pattern of recurrences must be considered along with such factors as age, demographics, travel, sexual history (including abuse), and immune status. Worldwide, syphilis, chancroid, lymphogranuloma venerum, and granuloma inguinale are the most common causes of vulvar ulcers.2 In North America, the most common cause, by far, is HSV (Table I).
Because the differential diagnosis is extensive, the evaluation of
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Cited by (61)
Ulcus vulvae acutum - A case of genital ulcers in adolescent girl
2016, Case Reports in Women's HealthCitation Excerpt :Infectious causes like HSV, Syphilis, lymphogranuloma venereum, chancroid and HIV should be considered in young patients who are sexually active, being HSV etiology the most common and potentially also non sexually-transmitted. HSV-PCR assay is thus the first step in the management of vulvar ulcers [[4,5] JEADV 2004, Mayo 2010]. Instead, when a documented sexually transmitted infectious etiology lacks or in the presence of a virgin female, other infective agents are to be considered besides inflammatory, autoimmune, traumatic and neoplastic causes [6].
Vulvar Ulcers: An Algorithm to Assist With Diagnosis and Treatment
2024, Journal of Lower Genital Tract DiseaseLipschütz Ulcer and SARS-CoV-2: What We Currently Know?
2023, DiseasesRecurrence of non-sexually acquired acute genital ulceration following COVID-19 vaccination
2023, Dermatology Online JournalTHE VULVA & VAGINA MANUAL
2023, The Vulva and Vagina Manual
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Funding sources: None.
Conflicts of interest: None identified.