Abstract
Diarrhea caused by enterotoxigenic E.coli (ETEC) is an important health problem in developing countries and in travelers to these areas. In previous trials formulations of ETEC vaccines containing the B-subunit of cholera toxin, which is antigenically similar to the heat labile enterotoxin of ETEC, and the most prevalent colonization factor antigens of ETEC, were shown to stimulate relevant mucosal immune responses in volunteers from Sweden and Egypt.
Publication types
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Clinical Trial
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Randomized Controlled Trial
MeSH terms
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Adult
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Austria
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Bacterial Vaccines* / adverse effects
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Bacterial Vaccines* / standards
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Child
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Cholera Toxin / immunology
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Cholera Vaccines / adverse effects
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Cholera Vaccines / standards
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Diarrhea / prevention & control*
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Double-Blind Method
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Escherichia coli / immunology*
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Feces / microbiology
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Female
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Humans
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Male
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Pilot Projects
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Travel*
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Vaccines, Combined
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Vaccines, Inactivated
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Vibrio cholerae / immunology*
Substances
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Bacterial Vaccines
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Cholera Vaccines
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Vaccines, Combined
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Vaccines, Inactivated
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Cholera Toxin