Abstract
In a randomized, double-blind controlled trial, 42 children with irritable bowel syndrome (IBS) were given pH-dependent, enteric-coated peppermint oil capsules or placebo. After 2 weeks, 75% of those receiving peppermint oil had reduced severity of pain associated with IBS. Peppermint oil may be used as a therapeutic agent during the symptomatic phase of IBS.
Publication types
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Clinical Trial
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Multicenter Study
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Randomized Controlled Trial
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Research Support, Non-U.S. Gov't
MeSH terms
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Abdominal Pain / diagnosis
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Abdominal Pain / etiology
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Adolescent
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Age Factors
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Child
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Colonic Diseases, Functional / complications
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Colonic Diseases, Functional / drug therapy*
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Colonic Diseases, Functional / physiopathology
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Double-Blind Method
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Female
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Humans
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Hydrogen-Ion Concentration
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Male
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Mentha piperita
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Pain Measurement
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Parasympatholytics / therapeutic use*
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Plant Oils / therapeutic use*
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Severity of Illness Index
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Tablets, Enteric-Coated / therapeutic use*
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Treatment Outcome
Substances
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Parasympatholytics
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Plant Oils
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Tablets, Enteric-Coated
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peppermint oil