Guttate morphoea in human T-cell lymphoma/lymphotrophic virus type-1 (HTLV-1) infection

Clin Exp Dermatol. 2003 Jul;28(4):380-2. doi: 10.1046/j.1365-2230.2003.01298.x.

Abstract

A 62-year-old Japanese man presented with multiple small atrophic macules on the trunk and extremities. The lesions were discrete, oval in shape and enclosed by lilac ring. They were distributed in a Christmas tree distribution, reminiscent of pityriasis rosea. Skin biopsy showed increased collagen fibres in the dermis and invading subcutaneous tissue. The clinico-pathological features were consistent with guttate morphoea, a rare variant of localized scleroderma. Serological tests revealed a positive reaction to human T-cell lymphoma/lymphotropic virus type-1 infection.

Publication types

  • Case Reports

MeSH terms

  • Biopsy
  • Collagen Type I / metabolism
  • Human T-lymphotropic virus 1
  • Humans
  • Leukemia-Lymphoma, Adult T-Cell / complications*
  • Male
  • Middle Aged
  • Scleroderma, Localized / pathology
  • Scleroderma, Localized / virology*
  • Serologic Tests
  • Skin Diseases, Viral / complications*
  • Transforming Growth Factor beta
  • Transforming Growth Factor beta1

Substances

  • Collagen Type I
  • TGFB1 protein, human
  • Transforming Growth Factor beta
  • Transforming Growth Factor beta1