Important bacterial gastrointestinal pathogens in children: a pathogenesis perspective

Pediatr Clin North Am. 2005 Jun;52(3):749-77, vi. doi: 10.1016/j.pcl.2005.03.002.

Abstract

This article focuses on the five most common bacterial enteropathogens of the developed world--Helicobacter pylori, Escherichia coli, Shigella, Salmonella, and Campylobacter--from the perspective of how they cause disease and how they relate to each other. Basic and recurring themes of bacterial pathogenesis, including mechanisms of entry, methods of adherence, sites of cellular injury, role of toxins, and how pathogens acquire particular virulence traits (and antimicrobial resistance), are discussed.

Publication types

  • Review

MeSH terms

  • Anti-Bacterial Agents / therapeutic use*
  • Bacterial Infections / diagnosis
  • Bacterial Infections / drug therapy
  • Bacterial Infections / epidemiology
  • Bacterial Infections / microbiology*
  • Campylobacter Infections / microbiology
  • Cell Adhesion
  • Child
  • Child Welfare* / statistics & numerical data
  • Developed Countries
  • Drug Resistance, Bacterial
  • Dysentery, Bacillary / microbiology
  • Escherichia coli / pathogenicity
  • Escherichia coli Infections / microbiology
  • Gastroenteritis / diagnosis
  • Gastroenteritis / drug therapy
  • Gastroenteritis / epidemiology
  • Gastroenteritis / microbiology*
  • Helicobacter Infections / microbiology
  • Helicobacter pylori / pathogenicity
  • Humans
  • Microbial Sensitivity Tests
  • Pediatrics / methods*
  • Salmonella Infections / microbiology

Substances

  • Anti-Bacterial Agents