Objective: To describe the first reported case of a triplet pregnancy subsequent to the use of an aromatase inhibitor for ovulation induction.
Design: Case report.
Setting: Academic medical center.
Patient(s): A 32-year-old female with polycystic ovary syndrome and primary infertility.
Intervention(s): Letrozole, 5 mg/day, on cycle days 2 to 6 for ovulation induction.
Main outcome measure(s): Clinical pregnancy.
Result(s): Viable triplet gestation.
Conclusion(s): Use of an aromatase inhibitor for ovulation induction does not eliminate the risk for higher order multiple pregnancy.