Late onset of a facial variant of steatocystoma multiplex - calretinin as a specific marker of the follicular companion cell layer

J Dtsch Dermatol Ges. 2008 Jun;6(6):480-2. doi: 10.1111/j.1610-0387.2007.06603.x.
[Article in English, German]

Abstract

Steatocystoma multiplex is a rare,almost exclusively autosomal dominant disease of the sebaceous glands. The sites of predilection are the sternal region, upper back, axillae and proximal parts of the extremities. A 78-year-old woman developed multiple yellowish nodules only on the face over a few months. Histology revealed large cysts with a thin wall and connection to sebaceous glands. Immunohistochemical analysis showed the inner epithelial layer of the cysts was positive with calretinin.With curettage and CO2 laser therapy, a good cosmetic result was achieved.This is the first case report in the German literature of a rare sporadic form of steatocystoma multiplex with late onset and exclusive localization in the face.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Biomarkers / analysis
  • Calbindin 2
  • Facial Dermatoses / diagnosis*
  • Facial Dermatoses / therapy
  • Female
  • Hair Follicle / metabolism*
  • Hair Follicle / pathology*
  • Humans
  • Rare Diseases / diagnosis
  • Rare Diseases / therapy
  • S100 Calcium Binding Protein G / analysis*
  • Sebaceous Gland Diseases / diagnosis*
  • Sebaceous Gland Diseases / therapy

Substances

  • Biomarkers
  • CALB2 protein, human
  • Calbindin 2
  • S100 Calcium Binding Protein G