Discordance between Staphylococcus aureus nasal colonization and skin infections in children

Pediatr Infect Dis J. 2009 Mar;28(3):244-6. doi: 10.1097/INF.0b013e31818cb0c4.

Abstract

We examined nasal carriage of Staphylococcus aureus in otherwise healthy children presenting with skin and soft tissue infections. We found high rates of nasal colonization with S. aureus, but significant discordance between nasal and wound isolates. Recurrent skin and soft tissue infections were common but unrelated to baseline methicillin-resistant S. aureus nasal colonization status.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Anti-Bacterial Agents / pharmacology
  • Carrier State / epidemiology*
  • Carrier State / microbiology*
  • Child
  • Child, Preschool
  • Electrophoresis, Gel, Pulsed-Field
  • Humans
  • Infant
  • Methicillin / pharmacology
  • Methicillin-Resistant Staphylococcus aureus / drug effects
  • Methicillin-Resistant Staphylococcus aureus / genetics
  • Methicillin-Resistant Staphylococcus aureus / isolation & purification*
  • Microbial Sensitivity Tests
  • Nasal Cavity / microbiology*
  • Soft Tissue Infections / epidemiology
  • Soft Tissue Infections / microbiology
  • Staphylococcal Infections / epidemiology
  • Staphylococcal Infections / microbiology
  • Staphylococcal Skin Infections / epidemiology*
  • Staphylococcal Skin Infections / microbiology
  • Staphylococcus aureus / drug effects
  • Staphylococcus aureus / genetics
  • Staphylococcus aureus / isolation & purification*
  • Wound Infection / epidemiology
  • Wound Infection / microbiology

Substances

  • Anti-Bacterial Agents
  • Methicillin