Abstract
Kawasaki disease is a systemic vasculitis and the leading cause of acquired heart disease in North American and Japanese children. The epidemiology, cause, and clinical characteristics of this disease are reviewed. The diagnostic challenge of Kawasaki disease and its implications for coronary artery outcomes are discussed, as are the recommended treatment, ongoing treatment controversies, concerns associated with treatment resistance, and the importance of ongoing follow up.
Copyright © 2012 Elsevier Inc. All rights reserved.
MeSH terms
-
Adrenal Cortex Hormones / therapeutic use
-
Anti-Inflammatory Agents / therapeutic use
-
Anti-Inflammatory Agents, Non-Steroidal / therapeutic use
-
Aspirin / therapeutic use
-
Child
-
Humans
-
Immunoglobulins, Intravenous / therapeutic use
-
Immunologic Factors / therapeutic use
-
Mucocutaneous Lymph Node Syndrome* / diagnosis
-
Mucocutaneous Lymph Node Syndrome* / drug therapy
-
Mucocutaneous Lymph Node Syndrome* / epidemiology
-
Mucocutaneous Lymph Node Syndrome* / etiology
-
Risk Factors
Substances
-
Adrenal Cortex Hormones
-
Anti-Inflammatory Agents
-
Anti-Inflammatory Agents, Non-Steroidal
-
Immunoglobulins, Intravenous
-
Immunologic Factors
-
Aspirin