The influence of S-adenosylmethionine (SAM) on prolactin in depressed patients

Int Clin Psychopharmacol. 1987 Apr;2(2):97-102. doi: 10.1097/00004850-198704000-00001.

Abstract

Twenty subjects entered a double-blind placebo-controlled trial of SAM in depression. Prolactin concentrations were measured before and after 14 days' treatment. There was a highly significant fall in prolactin concentrations in the SAM-treated group.

Publication types

  • Clinical Trial
  • Controlled Clinical Trial
  • Randomized Controlled Trial

MeSH terms

  • Adult
  • Aged
  • Clinical Trials as Topic
  • Depressive Disorder / blood
  • Depressive Disorder / drug therapy*
  • Double-Blind Method
  • Female
  • Humans
  • Male
  • Middle Aged
  • Prolactin / blood*
  • Psychiatric Status Rating Scales
  • S-Adenosylmethionine / therapeutic use*

Substances

  • S-Adenosylmethionine
  • Prolactin