Circulating cell-free DNA (cfDNA) has been suggested as a cancer biomarker. Several studies
assessed the usefulness of quantitative and qualitative tumor-specific alterations of cfDNA…

Using quantitative reverse transcription–polymerase chain reaction (RT-PCR), reference
genes are utilized as endogenous controls for relative quantification of target genes in gene …

Three-dimensional tumor models have become established in both basic and clinical research.
As multicellular systems consisting of tumor and tumor-associated cells, they can better …

Purpose : Prostate specific membrane antigen is expressed by the endothelium of many
tumors. The aim of the study was to find a rationale for prostate specific membrane antigen …

Apoptosis is a highly conserved biochemical mechanism which is tightly controlled in cells.
It contributes to maintenance of tissue homeostasis and normally eliminates highly …

Background Due to the poor prognosis for advanced renal cell carcinoma (RCC), there is
an urgent need for new therapeutic targets and for prognostic markers to identify high risk …

Epigenetic modifications and microRNAs are known to play key roles in human cancer. For
urological tumors, changes in epigenetic modifications and aberrant microRNA profiles have …

Extracellular matrix (ECM) provides a scaffold for cells and tissues, but also supports
organogenesis and tissue remodeling. The required instructive properties of the ECM to interact …

The selection of pluripotent stem cell (PSC)‐derived cells for tissue modeling and cell therapy
will be influenced by their response to the tissue environment, including the extracellular …

Grainyhead transcription factors control epithelial barriers, tissue morphogenesis, and
differentiation, but their role in the kidney is poorly understood. Here, we report that nephric duct, …