Life threatening hyperkalaemia (> 7.0 mmol/l ) is commonly associated with acute renal failure.
Moderate hyperkalaemia ( 6.1–6.9 mmol/l ) is also common and well tolerated in patients …

Proteinaceous inclusions with amyloidogenic properties are a common link between many
neurodegenerative diseases, including Alzheimer's disease and Parkinson's disease. …

Tau is a microtubule‐associated protein that promotes microtubule assembly and stability.
In Alzheimer’s disease and related tauopathies, tau fibrillizes and aggregates into …

Background. Muscle dysfunction, which contributes to morbidity in patients on haemodialysis,
has several manifestations and a number of possible causes. We applied the non-invasive …

Alzheimer disease and several other neurodegenerative disorders are characterized by the
accumulation of intraneuronal fibrils comprised of the protein Tau. Tau is normally a soluble …

The microtubule (MT)–stabilizing protein tau disengages from MTs and forms intracellular
inclusions known as neurofibrillary tangles in Alzheimer’s disease and related tauopathies. …

BACKGROUND: Renal allograft outcome, during an 8 year period (1985-1992), has been
assessed in 56 renal transplants performed in 55 patients who had end-stage renal failure as …

A library of ∼51,000 compounds was interrogated by high throughput screening (HTS) using
a heparin-induced tau fibrillization assay. HTS was conducted with bacterially expressed …

Inclusions comprised of fibrils of the microtubule- (MT-) associated protein tau are found in
the brains of those with Alzheimer’s disease (AD) and other neurodegenerative tauopathies. …

The microtubule-associated protein tau forms insoluble filaments that deposit as neurofibrillary
tangles (NFTs) in the brains of those with Alzheimer's disease (AD) and other related …