Since the publication of the 2012 guidelines new literature has emerged to inform decision-making.
The 2016 guidelines primary panel selected a number of clinically relevant …

The 2021 guidelines primary panel selected clinically relevant questions and produced
updated recommendations, on the basis of important new findings that have emerged since the …

Objective To summarize the pathophysiology, epidemiology, screening, diagnosis, and
treatment of familial hypercholesterolemia (FH). Quality of evidence A PubMed search was …

Tacrolimus is a commonly used immunosuppressive agent in renal transplantation.
Therapeutic drug monitoring of tacrolimus is recommended because it demonstrates wide …

Aims The aim of this study was to synthesize the evidence on the effect of heart failure with
reduced ejection fraction (HFrEF) pharmacotherapy on health‐related quality of life (HRQoL). …

Introduction Patients' lack of knowledge is a key barrier to therapy adherence. We aimed to
gather insights into atrial fibrillation (AF) patients' education needs from patient and clinician …

Background Conventional adherence summary measures do not capture the dynamic
nature of adherence. Objectives This study aims to characterize distinct long-term oral …

Background: Despite a lack of good scientific evidence for their benefit, Canadians take a
lot of natural health products (NHPs). The objectives of this study were to determine patients’ …

Background: A recent trend among health care professionals is the use of social media for
professional purposes. These rapidly expanding media allow for timely and efficient access to …

Beta‐blockers are recommended as standard of care for patients who experience a myocardial
infarction ( MI ). However, evidence to support this recommendation is primarily derived …