Filaggrin in the frontline: role in skin barrier function and disease
A Sandilands, C Sutherland, AD Irvine… - Journal of cell …, 2009 - journals.biologists.com
… However, in rat and mouse profilaggrin, the C-terminal domain is much smaller and … During
processing, the N-terminal and C-terminal domains are cleaved from the parent profilaggrin …
processing, the N-terminal and C-terminal domains are cleaved from the parent profilaggrin …
[HTML][HTML] What Are the bona fide GSK3 Substrates?
C Sutherland - International journal of Alzheimer's Disease, 2011 - hindawi.com
… described GSK3 substrates require pre-phosphorylation at a residue 4 or 5 amino acids C-…
%, demonstrating the importance of the phosphorylated residue C-terminal to the target site. …
%, demonstrating the importance of the phosphorylated residue C-terminal to the target site. …
The epidemiology of Plasmodium falciparum gametocytes: weapons of mass dispersion
C Drakeley, C Sutherland, JT Bousema… - Trends in …, 2006 - cell.com
Much of the epidemiology of Plasmodium falciparum in Sub-Saharan Africa focuses on the
prevalence patterns of asexual parasites in people of different ages, whereas the …
prevalence patterns of asexual parasites in people of different ages, whereas the …
[PDF][PDF] ULBPs, novel MHC class I–related molecules, bind to CMV glycoprotein UL16 and stimulate NK cytotoxicity through the NKG2D receptor
D Cosman, J Müllberg, CL Sutherland, W Chin… - Immunity, 2001 - cell.com
… extracellular domains were fused at their C termini to a modified leucine zipper motif with a
hexahistidine tag may not always predict protein expression. ULBP3 expression was highest …
hexahistidine tag may not always predict protein expression. ULBP3 expression was highest …
Inactivation of glycogen synthase kinase-3β by phosphorylation: new kinase connections in insulin and growth-factor signalling
C Sutherland, IA Leighton, P Cohen - Biochemical Journal, 1993 - portlandpress.com
… Subsequently, it was implicated in the phosphorylation of transcription factors, such as c-jun
and c-myc [4-7], and in the regulation of several developmental processes in Drosophila [8,9]…
and c-myc [4-7], and in the regulation of several developmental processes in Drosophila [8,9]…
Dendritic cell survival and maturation are regulated by different signaling pathways
M Rescigno, M Martino, CL Sutherland… - The Journal of …, 1998 - rupress.org
Although dendritic cell (DC) activation is a critical event for the induction of immune responses,
the signaling pathways involved in this process have not been characterized. In this report…
the signaling pathways involved in this process have not been characterized. In this report…
A ten-year follow-up of one hundred consecutive Müller curved-stem total hip-replacement arthroplasties.
CJ Sutherland, AH Wilde, LS Borden, KE Marks - JBJS, 1982 - journals.lww.com
One hundred consecutive Müller curved-stem total hip replacements were reviewed ten
years after operation. Twenty patients with twenty-two arthroplasties had died within the ten-year …
years after operation. Twenty patients with twenty-two arthroplasties had died within the ten-year …
[HTML][HTML] A Worldwide Map of Plasmodium falciparum K13-Propeller Polymorphisms
…, KD Silué, SB Sirima, C Sutherland… - … England Journal of …, 2016 - Mass Medical Soc
Background Recent gains in reducing the global burden of malaria are threatened by the
emergence of Plasmodium falciparum resistance to artemisinins. The discovery that mutations …
emergence of Plasmodium falciparum resistance to artemisinins. The discovery that mutations …
[HTML][HTML] Analysis of Plasmodium falciparum diversity in natural infections by deep sequencing
…, C Hubbart, A Jeffreys, K Rowlands, C Sutherland… - Nature, 2012 - nature.com
Malaria elimination strategies require surveillance of the parasite population for genetic
changes that demand a public health response, such as new forms of drug resistance 1 , 2 . …
changes that demand a public health response, such as new forms of drug resistance 1 , 2 . …
Two Nonrecombining Sympatric Forms of the Human Malaria Parasite Plasmodium ovale Occur Globally
CJ Sutherland, N Tanomsing, D Nolder… - The Journal of …, 2010 - academic.oup.com
Background . Malaria in humans is caused by apicomplexan parasites belonging to 5 species
of the genus Plasmodium. Infections with Plasmodium ovale are widely distributed but …
of the genus Plasmodium. Infections with Plasmodium ovale are widely distributed but …