Rates of teenage pregnancies are higher for African American and Latina adolescents
compared to their White peers. African American and Latina adolescent mothers also experience …

The transcriptional regulation of neuroectoderm (NE) specification is unknown. Here we
show that Pax6 is uniformly expressed in early NE cells of human fetuses and those …

BACKGROUND: Elderly individuals with chronic kidney disease (CKD) have high rates of
comorbid conditions, including cardiovascular disease and its risk factors, and CKD-related …

Microglia are emerging as key drivers of neurological diseases. However, we lack a systematic
understanding of the underlying mechanisms. Here, we present a screening platform to …

A higher body mass index is associated with better outcomes in hemodialysis patients; however,
this index does not differentiate between fat and muscle mass. In order to clarify this, we …

Precise temporal control of gene expression or deletion is critical for elucidating gene
function in biological systems. However, the establishment of human pluripotent stem cell (hPSC) …

Serotonin neurons located in the raphe nucleus of the hindbrain have crucial roles in regulating
brain functions and have been implicated in various psychiatric disorders. Yet functional …

Synaptic plasticity, the cellular correlate for learning and memory, involves signaling cascades
in the dendritic spine. Extensive studies have shown that long-term potentiation (LTP) of …

Advancements in robotic technology are making it increasingly possible to integrate robots
into the human workspace in order to improve productivity and decrease worker strain …

Postnatal and adult human and monkey fibroblasts were infected with Sendai virus containing
the Yamanaka factors for 24 hr, then they were cultured in a chemically defined medium …