User profiles for J Pilla

James J Pilla

University of Pennsylvania
Verified email at uphs.upenn.edu
Cited by 2077

A technique for in vivo mapping of myocardial creatine kinase metabolism

…, GA Zsido, WRT Witschey, K Koomalsingh, JJ Pilla… - Nature medicine, 2014 - nature.com
ATP derived from the conversion of phosphocreatine to creatine by creatine kinase provides
an essential chemical energy source that governs myocardial contraction. Here, we …

Injectable shear-thinning hydrogels for minimally invasive delivery to infarcted myocardium to limit left ventricular remodeling

…, SM Dorsey, WRT Witschey, JJ Pilla… - Circulation …, 2016 - Am Heart Assoc
Background— Injectable, acellular biomaterials hold promise to limit left ventricular remodeling
and heart failure precipitated by infarction through bulking or stiffening the infarct region. …

MRI evaluation of injectable hyaluronic acid-based hydrogel therapy to limit ventricular remodeling after myocardial infarction

…, KJ Koomalsingh, N Kondo, JH Gorman III, JJ Pilla… - Biomaterials, 2015 - Elsevier
Injectable biomaterials are an attractive therapy to attenuate left ventricular (LV) remodeling
after myocardial infarction (MI). Although studies have shown that injectable hydrogels …

[HTML][HTML] In vivo chronic myocardial infarction characterization by spin locked cardiovascular magnetic resonance

…, JR McGarvey, MM Levack, F Contijoch, JJ Pilla… - Journal of …, 2012 - Springer
Background Late gadolinium enhanced (LGE) cardiovascular magnetic resonance (CMR) is
frequently used to evaluate myocardial viability, estimate total infarct size and transmurality, …

[HTML][HTML] Second international consensus report on gaps and opportunities for the clinical translation of precision diabetes medicine

…, J Most, RN Naylor, B Ozkan, KA Patel, SJ Pilla… - Nature medicine, 2023 - nature.com
Precision medicine is part of the logical evolution of contemporary evidence-based medicine
that seeks to reduce errors and optimize outcomes when making medical decisions and …

Cardiac support device modifies left ventricular geometry and myocardial structure after myocardial infarction

AS Blom, R Mukherjee, JJ Pilla, AS Lowry… - Circulation, 2005 - Am Heart Assoc
Background— Whether mechanical restraint of the left ventricle (LV) can influence remodeling
after myocardial infarction (MI) remains poorly understood. This study surgically placed a …

Accuracy of ICD–9–CM codes in hospital morbidity data, Victoria: implications for public health research

…, MJ Ackland, EJ Chandraraj, JE Pilla - Australian and New …, 1997 - Wiley Online Library
Hospital morbidity data in the form of International classification of diseases, 9th revision,
clinical modification codes are often used for epidemiological studies and disease surveillance. …

Estimating passive mechanical properties in a myocardial infarction using MRI and finite element simulations

…, SM Dorsey, JH Gorman, JA Burdick, JJ Pilla… - … and modeling in …, 2015 - Springer
Myocardial infarction (MI) triggers a series of maladaptive events that lead to structural and
functional changes in the left ventricle. It is crucial to better understand the progression of …

[HTML][HTML] Iron imaging in myocardial infarction reperfusion injury

…, A Tsourkas, A Imai, K Okamoto, Y Saito, JJ Pilla… - Nature …, 2020 - nature.com
Restoration of coronary blood flow after a heart attack can cause reperfusion injury potentially
leading to impaired cardiac function, adverse tissue remodeling and heart failure. Iron is …

Noninvasive measurement of the human brachial artery pressure–area relation in collapse and hypertension

G Drzewiecki, JJ Pilla - Annals of biomedical engineering, 1998 - Springer
A noninvasive method to obtain pressure–lumen area (PA) measurements of the human
brachial artery is introduced. The data obtained from this method are analyzed using a …