Objective We reviewed the current literature regarding antiretroviral (ARV)-sparing therapy
strategies to determine whether these novel regimens can be considered appropriate …

There is increasing evidence that chronic obstructive pulmonary disease (COPD) is associated
with chronic inflammation in the airways and lung parenchyma; however, little is known …

In vitro, IL-10 inhibits T cell proliferation and LPS-induced monocyte production of IL-1, TNF-alpha,
IL-6, and IL-8. We studied the safety and immunomodulatory effects of IL-10 …

While only partial immune reconstitution in gut-associated lymphoid tissue typically occurs
following initiation of highly active antiretroviral therapy (HAART) in human immunodeficiency …

Background Cabotegravir and rilpivirine are antiretroviral drugs in development as long-acting
injectable formulations. The LATTE-2 study evaluated long-acting cabotegravir plus …

Sequence variants at or near the leucine-rich repeat kinase 2 (LRRK2) locus have been
associated with susceptibility to three human conditions: Parkinson's disease (PD), Crohn’s …

Background: HIV patients are vaccine hyporesponsive. Methods: We evaluated CPG 7909,
a synthetic oligodeoxynucleotide containing immunostimulatory CpG motifs, as an adjuvant …

Background Improvements in life expectancy and quality of life for HIV-positive women
coupled with reduced vertical transmission will likely lead numerous HIV-positive women to …

Objective: To evaluate the safety and antiretroviral activity of ritonavir (Norvir TM) and saquinavir
(Invirase TM) combination therapy in patients with HIV infection. Design: A multicenter, …

Background . Reactivation of hepatitis B virus (HBV) infection following allogeneic bone
marrow transplantation is a rare phenomenon. Methods . Reverse seroconversion, defined as …