The coronavirus disease 2019 (COVID-19) pandemic—and the social distancing measures
that many countries have implemented—have caused disruptions to daily routines. As of …

High-quality and complete reference genome assemblies are fundamental for the application
of genomics to biology, disease, and biodiversity conservation. However, such assemblies …

Acute exacerbation of idiopathic pulmonary fibrosis has been defined as an acute, clinically
significant, respiratory deterioration of unidentifiable cause. The objective of this …

Background: Idiopathic pulmonary fibrosis (IPF) is a progressive fibrotic lung disease with an
overall poor prognosis. A simple-to-use staging system for IPF may improve prognostication…

To systematically elucidate the effect of surface charge on the cellular uptake and in vivo
fate of PEG-oligocholic acid based micellar nanoparticles (NPs), the distal PEG termini of …

Epigenetic alterations have contributed greatly to human carcinogenesis. Conventional
epigenetic studies have predominantly focused on DNA methylation, histone modifications, and …

Background Hepatocellular carcinoma is a common and aggressive cancer that occurs mainly
in men. We examined microRNA expression patterns, survival, and response to interferon …

Many patients with an idiopathic interstitial pneumonia (IIP) have clinical features that suggest
an underlying autoimmune process but do not meet established criteria for a connective …

Adeno-associated virus (AAV) serotypes differ broadly in transduction efficacies and tissue
tropisms and thus hold enormous potential as vectors for human gene therapy. In reality, …

INTRODUCTION The characterization of the full spectrum of genetic variation is critical to
understanding human health and disease. Recent technological advances have made it …