User profiles for R. Zur

Richard Michael Zur

IQVIA
Verified email at iqvia.com
Cited by 737

[HTML][HTML] Efficacy and tolerability of mirabegron compared with antimuscarinic monotherapy or combination therapies for overactive bladder: a systematic review and …

C Kelleher, Z Hakimi, R Zur, E Siddiqui, K Maman… - European urology, 2018 - Elsevier
Background Mirabegron is an established treatment alternative to antimuscarinic therapy for
patients with overactive bladder (OAB), as shown by efficacy and tolerability data from …

The placental basis of fetal growth restriction

RL Zur, WT Parks, SR Hobson - Obstetrics and Gynecology …, 2020 - obgyn.theclinics.com
The past decade has seen a substantial advancement in our understanding of placental
diseases that are associated with fetal growth restriction (FGR). 1 This increased understanding …

A cell-based screen identifies ATR inhibitors with synthetic lethal properties for cancer-associated mutations

LI Toledo, M Murga, R Zur, R Soria… - Nature structural & …, 2011 - nature.com
Oncogene activation has been shown to generate replication-born DNA damage, also
known as replicative stress. The primary responder to replicative stress is not Ataxia-…

Noise injection for training artificial neural networks: A comparison with weight decay and early stopping

RM Zur, Y Jiang, LL Pesce, K Drukker - Medical physics, 2009 - Wiley Online Library
The purpose of this study was to investigate the effect of a noise injection method on the “overfitting”
problem of artificial neural networks (ANNs) in two‐class classification tasks. The …

6-thioguanine selectively kills BRCA2-defective tumors and overcomes PARP inhibitor resistance

…, I Stoimenov, S Kyle, N Pedley, P Gottipati, R Zur… - Cancer research, 2010 - AACR
Familial breast and ovarian cancers are often defective in homologous recombination (HR)
due to mutations in the BRCA1 or BRCA2 genes. Cisplatin chemotherapy or poly(ADP-ribose…

Implication of Akt, ERK1/2 and alternative p38MAPK signalling pathways in human colon cancer cell apoptosis induced by green tea EGCG

MI Cerezo-Guisado, R Zur, MJ Lorenzo, A Risco… - Food and Chemical …, 2015 - Elsevier
We investigated apoptosis induced by the green tea component the epigallocatechin-3-gallate
(EGCG) and the pathways underlying its activity in a colon cancer cell line. A complete …

Pro-oncogenic role of alternative p38 mitogen-activated protein kinases p38γ and p38δ, linking inflammation and cancer in colitis-associated colon cancer

…, MI Cerezo-Guisado, A Risco, N Aparicio, R Zur… - Cancer research, 2014 - AACR
p38 MAPK signaling has been implicated in the regulation of processes leading to cancer
development and progression. Chronic inflammation is a known risk factor for tumorigenesis, …

[HTML][HTML] A microcosting and cost–consequence analysis of clinical genomic testing strategies in autism spectrum disorder

K Tsiplova, RM Zur, CR Marshall, DJ Stavropoulos… - Genetics in …, 2017 - Elsevier
Purpose Whole-exome (WES) and whole-genome sequencing (WGS) increase the diagnostic
yield in autism spectrum disorder (ASD) compared to chromosomal microarray (CMA), but …

Credibility assessment in child sexual abuse investigations: A descriptive analysis

EP Melkman, I Hershkowitz, R Zur - Child abuse & neglect, 2017 - Elsevier
A major challenge in cases of child sexual abuse (CSA) is determining the credibility of
children's reports. Consequently cases may be misclassified as false or deemed ‘no judgment …

A study of the effect of noise injection on the training of artificial neural networks

Y Jiang, RM Zur, LL Pesce… - 2009 International Joint …, 2009 - ieeexplore.ieee.org
We studied the effect of noise injection in overcoming the problem of overtraining in the
training of artificial neural networks (ANNs) in comparison with other common approaches for …