User profiles for S. C. Shen

Shixin (Cindy) Shen

University of Toronto
Verified email at mail.utoronto.ca
Cited by 509

Addressing vaccine hesitancy: Clinical guidance for primary care physicians working with parents

SC Shen, V Dubey - Canadian Family Physician, 2019 - cfp.ca
Objective To provide primary care physicians with clinical guidance for addressing parental
vaccine hesitancy. Sources of information The PubMed database was searched for English-…

[HTML][HTML] Tape-Arabidopsis Sandwich - a simpler Arabidopsis protoplast isolation method

FH Wu, SC Shen, LY Lee, SH Lee, MT Chan, CS Lin - Plant methods, 2009 - Springer
Background Protoplasts isolated from leaves are useful materials in plant research. One
application, the transient expression of recombinant genes using Arabidopsis mesophyll …

Hand-arm vibration syndrome: What family physicians should know

SC Shen, RA House - Canadian Family Physician, 2017 - cfp.ca
Objective To provide family physicians with an understanding of the epidemiology, pathogenesis,
symptoms, diagnosis, and management of hand-arm vibration syndrome (HAVS), an …

Wogonin, baicalin, and baicalein inhibition of inducible nitric oxide synthase and cyclooxygenase-2 gene expressions induced by nitric oxide synthase inhibitors and …

YC Chen, SC Shen, LG Chen, TJF Lee… - Biochemical …, 2001 - Elsevier
We previously reported that oroxylin A, a polyphenolic compound, was a potent inhibitor of
lipopolysaccharide (LPS)-induced expression of inducible nitric oxide synthase (iNOS) and …

Inhibition of nitric oxide synthase inhibitors and lipopolysaccharide induced inducible NOS and cyclooxygenase‐2 gene expressions by rutin, quercetin, and quercetin …

YC Chen, SC Shen, WR Lee, WC Hou… - Journal of cellular …, 2001 - Wiley Online Library
Several natural flavonoids have been demonstrated to perform some beneficial biological
activities, however, higher‐effective concentrations and poor‐absorptive efficacy in body of …

Quercetin, but not rutin and quercitrin, prevention of H2O2-induced apoptosis via anti-oxidant activity and heme oxygenase 1 gene expression in macrophages

JM Chow, SC Shen, SK Huan, HY Lin… - Biochemical …, 2005 - Elsevier
In the present study, we examine the protective mechanism of quercetin (QE) on oxidative
stress-induced cytotoxic effect in RAW264.7 macrophages. Results of Western blotting show …

Emodin induces apoptosis in human promyeloleukemic HL-60 cells accompanied by activation of caspase 3 cascade but independent of reactive oxygen species …

YC Chen, SC Shen, WR Lee, FL Hsu, HY Lin… - Biochemical …, 2002 - Elsevier
Emodin (1,3,8-trihydroxy-6-methylanthraquinone) is an active constituent of Rheum
palmatum, and showed inhibitory activity on lipopolysaccharide-induced NO production in our …

In vitro and in vivo inhibitory activities of rutin, wogonin, and quercetin on lipopolysaccharide-induced nitric oxide and prostaglandin E2 production

SC Shen, WR Lee, HY Lin, HC Huang, CH Ko… - European journal of …, 2002 - Elsevier
Flavonoids are widely distributed in plants, but their biological functions are still unclear. In
the present study, in vitro and in vivo experiments were performed to demonstrate the …

Wogonin and fisetin induce apoptosis in human promyeloleukemic cells, accompanied by a decrease of reactive oxygen species, and activation of caspase 3 and …

WR Lee, SC Shen, HY Lin, WC Hou, LL Yang… - Biochemical …, 2002 - Elsevier
Seven structurally related flavonoids including luteolin, nobiletin, wogonin, baicalein, apigenin,
myricetin and fisetin were used to study their biological activities on the human leukemia …

A general synthesis of single atom catalysts with controllable atomic and mesoporous structures

ZY Wu, P Zhu, DA Cullen, Y Hu, QQ Yan, SC Shen… - Nature …, 2022 - nature.com
The control of single metal atomic sites has been extensively studied in the field of single
atom catalysts. By contrast, the precise control of the mesoporous structure in the matrix …