Glioblastoma is one of the most fatal cancers, characterized by a strong vascularized phenotype.
YKL-40, a secreted glycoprotein, is overexpressed in patients with glioblastomas and …

Purpose and scope The aim of this Position Statement is to provide recommendations for
Canadian medical geneticists, clinical laboratory geneticists, genetic counsellors and other …

Recent evidence has shown that glioblastoma stem-like cells (GSCs) can transdifferentiate
into endothelial cells and vascular-like tumor cells. The latter pattern of vascularization …

Glioblastoma (GBM) is extremely aggressive and essentially incurable. Its malignancy is
characterized by vigorous microvascular proliferations. Recent evidence has shown that tumor …

Abstract Analysis of 78 Huntington's disease (HD) chromosomes with multi–allele markers
revealed 26 different haplotypes, suggesting a variety of independent HD mutations. The …

OBJECTIVE To increase primary care providers’ awareness and use of genetic services;
increase their knowledge of genetic issues; increase their confidence in core genetic …

HYPONATREMIA IS RARELY reported as a delayed complication of transsphenoidal
resection of pituitary adenoma. Usually attributed to the syndrome of inappropriate secretion of …

Malignant glioblastomas (GBM) are highly malignant brain tumors that have extensive and
aberrant tumor vasculature, including multiple types of vessels. This review focuses on recent …

Chemo/radiotherapies are the most common adjuvant modality treated for patients with
glioblastoma (GBM) following surgery. However, the overall therapeutic benefits are still …

Background The methylation of DNA is recognized as a key mechanism in the regulation of
genomic stability and evidence for its role in the development of cancer is accumulating. LINE…