User profiles for Tarek Afifi

Tarek H Afifi

Taibah Unversity and Al-Azhar University
Verified email at taibahu.edu.sa
Cited by 1287

[HTML][HTML] Development of polyvinyl alcohol/kaolin sponges stimulated by marjoram as hemostatic, antibacterial, and antioxidant dressings for wound healing promotion

TM Tamer, MH Alsehli, AM Omer, TH Afifi… - International journal of …, 2021 - mdpi.com
The predominant impediments to cutaneous wound regeneration are hemorrhage and
bacterial infections that lead to extensive inflammation with lethal impact. We thus developed a …

Remarkable effect of copper chloride on diiodination of zirconacyclopentadienes

C Xi, S Huo, TH Afifi, R Hara, T Takahashi - Tetrahedron letters, 1997 - Elsevier
Treatment of zirconacyclopentadienes with two equiv of iodine in THF in the presence of 1.0
equiv of CuCl gave diiododienes in good to high yields without formation of monoiododienes…

[HTML][HTML] Design of New Benzo[h]chromene Derivatives: Antitumor Activities and Structure-Activity Relationships of the 2,3-Positions and Fused Rings at the 2,3 …

RM Okasha, FF Alblewi, TH Afifi, A Naqvi, AM Fouda… - Molecules, 2017 - mdpi.com
A series of novel 4H-benzo[h]chromenes 4, 6–11, 13, 14; 7H-benzo[h]chromeno[2,3-d]pyrimidines
15–18, 20, and 14H-benzo[h]chromeno[3,2-e][1,2,4]triazolo[1,5-c]pyrimidine …

Antiproliferative effect, cell cycle arrest and apoptosis generation of novel synthesized anticancer heterocyclic derivatives based 4H-benzo [h] chromene

…, A Mora, AM Fouda, MA Assiri, AAM Al-Dies, TH Afifi… - Bioorganic …, 2019 - Elsevier
Novel β-enaminonitrile/ester compounds (4, 6) and an imidate of 4 (9) were utilized as key
scaffolds for the synthesis of newly 2-substituted 4H-benzo[h]chromene (7, 8, 10, 11, 13, 14) …

[HTML][HTML] Structure-activity relationships and molecular docking studies of chromene and chromene based azo chromophores: A novel series of potent antimicrobial …

TH Afifi, RM Okasha, HEA Ahmed, J Ilaš, T Saleh… - EXCLI …, 2017 - ncbi.nlm.nih.gov
The design of novel materials with significant biological properties is a main target in drug
design research. Chromene compounds represent an interesting medicinal scaffold in drug …

Topical therapies for psoriasis: evidence-based review.

T Afifi, G de Gannes, C Huang, Y Zhou - Canadian family physician, 2005 - cfp.ca
OBJECTIVE To review current understandings of and approaches to topical psoriasis therapies
and to assess their efficacies and adverse effects. QUALITY OF EVIDENCE Literature …

Novel azo disperse dyes derived from aminothiophenes: Synthesis and UV–visible studies

AS Abd-El-Aziz, TH Afifi - Dyes and pigments, 2006 - Elsevier
A number of red to violet thienyl-2-azo and thienyl-5-azo disperse dyes were prepared using
Gewald's methodology. Structural characterization of these novel dyes was carried out …

Introducing novel potent anticancer agents of 1H-benzo[f]chromene scaffolds, targeting c-Src kinase enzyme with MDA-MB-231 cell line anti-invasion effect

…, RM Okasha, S Ihmaid, AM Fouda, TH Afifi… - Journal of Enzyme …, 2018 - Taylor & Francis
In our effort to develop novel and powerful agents with anti-proliferative activity, two new
series of 1H-benzo[f]chromene derivatives, 4a–h and 6a–h, were synthesised using …

Developing lipophilic aromatic halogenated fused systems with specific ring orientations, leading to potent anticancer analogs and targeting the c-Src Kinase enzyme

…, AM Fouda, AM El-Agrody, A Aljuhani, TH Afifi - Journal of Molecular …, 2019 - Elsevier
This work presents the combined microwave assisted synthesis, spectroscopic analyses,
cytotoxic effects, and molecular docking studies of the chromene fused ring systems with …

First example of Azo-Sulfa conjugated chromene moieties: Synthesis, characterization, antimicrobial assessment, docking simulation as potent class I histone …

…, SS Althagfan, MSA El-Gaby, HEA Ahmed, TH Afifi - Bioorganic …, 2019 - Elsevier
This report presents the development of a novel and primary model of sulfonamide compounds
encompassing a chromene azo motif with the intent of becoming applicable for drug …