Objective To quantify the risk of hyperkalemia and acute kidney injury (AKI) when
spironolactone use is added on to loop diuretic use among patients with heart failure, and to …

Conclusion: In India, many patients are from a low socioeconomic background and often
resort to cheap and filling food items like bananas. This dietary factor should be kept in mind …

Current evidence supports avoiding dual renin–angiotensin–aldosterone system blockade
in patients with chronic kidney disease. Subsequent studies of dual renin–angiotensin …

Despite numerous pharmacologic and nonpharmacologic treatment strategies, heart failure
remains a complex, progressive disorder with significant morbidity and mortality …

• RALES1: an RCT of 1663 patients with class III or IV HF taking ACEIs and diuretics;
patients received spironolactone or placebo. Results at 24 months:-A statistically significant …

In order to keep subscribers up‐to‐date with the latest developments in their field, John
Wiley & Sons are providing a current awareness service in each issue of the journal. The …

The aim: To evaluate the effect of single daily 25 mg of spironolactone on serum electrolytes
and kidney function tests in patients with severe chronic left sided heart failure. Materials …

Aims One prevalent comorbidity of chronic heart failure (CHF) is chronic kidney disease
(CKD). Hyperkalemia is associated with both CHF and CKD, which often leads to withdrawal …

Congenital heart defects are common congenital defects and they are major causes of death
in those with congenital malformation. 1, 2 Heart failure is a common complication thus all …

Cílem předložené disertační práce bylo zhodnotit interakce optických isomerů vybraných
chirálních léčiv s devíti formami nejdůležitějšího enzymatického aparátu metabolismu …