Abstract Approximately 5–10% of breast cancer cases might be inheritable, up to 30% of
which are due to BRCA1/2 mutations. During the past few years and thanks to technology …

Abstract Approximately 5–10% of breast cancers may be inheritable, up to 90% of which are
due to mutations in BRCA1 and BRCA2. A substantial minority are caused by non‐BRCA …

Abstract Human epididymis protein 4 (HE4) has recently been described as a new marker
for the early diagnosis of ovarian cancer (OC). The objective of this study was to evaluate (a) …

Background: Expert consensus on BRCA1/2 genetic testing and clinical application in
Chinese breast cancer patients recommends that BRCA1/2 testing should be performed in …

Breast cancer is one of the most common malignancies and the leading cause of death
among women worldwide. About 20% of breast cancers are hereditary. Approximately 30 …

Worldwide variation in the distribution of BRCA mutations is well recognised, and for the
Moroccan population no comprehensive studies about BRCA mutation spectra or …

Background. Patients look to their family physicians (FPs) for credible information and
guidance in making informed choices about genetic testing. FPs are challenged by lack of …

Introduction. Pakistani population has a very rich anthrogeneological background with
waves of migration from neighboring regions. Incidence rates of breast and ovarian cancer …

The primary goal of breast and ovarian cancer screening is to minimize the cases of
advanced disease and therefore its mortality rate. For hereditary breast and ovarian cancer …

Background Familial breast cancer accounts for 20–30% of all breast cancer cases.
Mutations in the BRCA1 and BRCA2 genes account for the majority of high risk families with …