The pharmacological importance of cannabinoids has been in study for several years.
Cannabinoids comprise of (a) the active compounds of the Cannabis sativa plant,(b) …

Bisphosphonates have found application in the treatment of reoccurrence of bone diseases,
breast cancer, etc. They have also been found to exhibit antimicrobial, anticancer and …

The need for bone repair and insight into new regeneration therapies as well as
improvement of existing regeneration routes is constantly increasing as a direct …

Bone cancer pain is a major clinical problem and remains difficult to treat. ATP-sensitive
potassium (K ATP) channels may be involved in regulating nociceptive transmission at the …

Bone metastases are the most common cause of pain in patients with advanced cancer, and
are associated with progressive skeletal destruction, spinal problems, and hypercalcaemia …

Denosumab is a fully human monoclonal antibody that binds to the receptor activator of
nuclear factor kappa-Β ligand, an essential cytokine factor in bone resorption, which reduces …

Bone is a common site of metastatic disease in both solid tumor and hematologic
malignancies. Skeletal involvement of cancer and the complications from these metastases …

Denosumab is a fully human monoclonal antibody that binds to the receptor activator of
nuclear factor kappa-Β ligand, an essential cytokine factor in bone resorption, which reduces …

Metastatic bone pain can be very severe and disabling. Effective management requires a
multi-modal multidisciplinary approach. Rennie (pseudonym), a 58-year-old lady was …

A wide array of tumors can occur in the sacrum. Benign tumors include giant cell tumors
(60%), aneurysmal bone cysts (4%), and osteoblastomas [1]. Malignant tumors of the …