Developing nociceptor-selective treatments for acute and chronic pain

S Jayakar, J Shim, S Jo, BP Bean, I Singeç… - Science translational …, 2021 - science.org
Despite substantial efforts dedicated to the development of new, nonaddictive analgesics,
success in treating pain has been limited. Clinically available analgesic agents generally …

Therapeutic strategies for postherpetic neuralgia: mechanisms, treatments, and perspectives

J Tang, Y Zhang, C Liu, A Zeng, L Song - Current Pain and Headache …, 2023 - Springer
Abstract Purpose of Review Postherpetic neuralgia is an annoying pain that mainly affects
older people. In order to give patients more options, this review summarizes the …

PEER simplified chronic pain guideline: Management of chronic low back, osteoarthritic, and neuropathic pain in primary care

CS Korownyk, L Montgomery, J Young, S Moore… - Canadian Family …, 2022 - cfp.ca
Objective To develop a clinical practice guideline to support the management of chronic
pain, including low back, osteoarthritic, and neuropathic pain in primary care. Methods The …

[HTML][HTML] The power of integrating data: advancing pain research using meta-analysis

J Fundaun, ET Thomas, AB Schmid, G Baskozos - Pain Reports, 2022 - journals.lww.com
Publications related to pain research have increased significantly in recent years. The
abundance of new evidence creates challenges staying up to date with the latest …

[HTML][HTML] Opioids and opioid receptors; understanding pharmacological mechanisms as a key to therapeutic advances and mitigation of the misuse crisis

DG Lambert - BJA open, 2023 - Elsevier
Opioids are a mainstay in acute pain management and produce their effects and side effects
(eg, tolerance, opioid-use disorder and immune suppression) by interaction with opioid …

Integrative health strategies to manage chronic pain

C Fogleman, K McKenna - Primary Care: Clinics in Office …, 2022 - primarycare.theclinics.com
Discussion While it is the rare individual in today's marketplace who would forgo the
opportunity to combine therapy options, given the choice and availability, complementary …

Non-pharmacological management of neuropathic pain in older adults: a systematic review

A Holmes, YP Chang - Pain Medicine, 2024 - academic.oup.com
Introduction Neuropathic pain encompasses multiple diagnoses with detrimental impacts on
quality of life and overall health. In older adults, pharmacological management is limited by …

Lignes directrices simplifiées de PEER sur la douleur chronique: Gestion de la douleur chronique lombaire, arthrosique et neuropathique en première ligne

CS Korownyk, L Montgomery, J Young, S Moore… - Canadian Family …, 2022 - cfp.ca
Objectif Formuler des lignes directrices de pratique clinique pour soutenir la prise en charge
de la douleur chronique, y compris la douleur lombaire, arthrosique et neuropathique, dans …

PEER simplified decision aid: neuropathic pain treatment options in primary care

K Chan, D Perry, AJ Lindblad, S Garrison, J Falk… - Canadian Family …, 2021 - cfp.ca
This decision aid is for clinicians for discussion of treatment options for patients living with
neuropathic pain. It is derived from our accompanying systematic review of randomized …

[PDF][PDF] Balancing needs and risks as the opioid pendulum swings

HC Barry - J Fam Pract, 2023 - cdn.mdedge.com
Recently, my family had a conversation about the volume of news reports on overdose
deaths from the illicit use of opioid drugs—a phenomenon that is complex and stems from …