Mrs P. is a 67-year-old woman with severe peripheral arterial disease. Her medical history
includes 32 pack-years of smoking, controlled hypertension, and type 2 diabetes mellitus …

Critical limb ischemia (CLI), the most advanced form of peripheral artery disease (PAD),
carries grave implications with regard to morbidity and mortality. This article is a …

Critical limb ischemia (CLI), which is at the end of the peripheral artery disease (PAD)
spectrum, is associated with excessively high risk for cardiovascular events, including …

Critical limb ischemia (CLI) has emerged as a major international public health challenge
that has so far only partially been met. CLI remains an undertreated condition with highly …

Opinion statement The need to develop highly qualified, multidisciplinary critical limb
ischemia (CLI) programs has gained significant momentum. Due to the systemic nature of …

This book provides a comprehensive overview of acute and chronic critical limb ischemia
(CLI). Loss of an extremity, or a portion thereof, is not necessarily a life-ending process, but it …

Consequently, several deadly cancers, such as melanoma or ovarian cancer, are actually
less common and less deadly than CLI. A helpful metric for quantifying the overall mortality …

BACKGROUND: Recommendations of clinical guidelines for the treatment of critical limb
ischemia (CLI) are based on randomized controlled trials. Recent data from clinical practice …

Atherosclerotic critical limb ischemia (CLI) is manifested by ischemic rest pain, non-healing
ulcers or gangrene. The incidence of CLI is estimated to be approximately 500-1000 new …

Chronic critical limb ischemia (CLI), defined as> 2 weeks of rest pain, ulcers, or tissue loss
attributed to arterial occlusive disease, is associated with great loss of both limb and life …