Approach to risk stratification of Atherosclerotic cardiovascular disease: use of biomarkers and imaging in a Canadian context

D Esau, BL Abramson - Canadian Family Physician, 2022 - cfp.ca
Objective To outline the 2021 Canadian Cardiovascular Society (CCS) dyslipidemia
guidelines and to present the current approaches to cardiovascular risk stratification …

Risk stratification and selection for statin therapy: going beyond framingham

DH Fitchett, GBJ Mancini, J Gregoire… - Canadian Journal of …, 2014 - Elsevier
Decisions for statin therapy in the primary prevention of atherosclerotic cardiovascular
disease are generally made using the 10-year Framingham Risk Score (FRS). Even when a …

[HTML][HTML] Primary and secondary prevention of atherosclerotic cardiovascular disease: A case-based approach

EH Hariri, MM Al Hammoud, SE Nissen… - Cleveland Clinic Journal …, 2022 - ccjm.org
Estimating the risk of atherosclerotic cardiovascular disease (ASCVD) is a daily challenge
for clinicians and is crucial to tailoring preventive medical care and guiding shared decision …

Accuracy of Pooled-Cohort Equation and SCORE cardiovascular risk calculators to identify individuals with high coronary atherosclerotic burden–implications for …

A Tralhão, AM Ferreira… - Coronary Artery …, 2016 - journals.lww.com
Background Different cardiovascular risk calculators and risk-based thresholds for initiating
statin therapy are currently in use. Using coronary computed tomography angiography, we …

The role of atherosclerosis imaging in redefining normal and abnormal cholesterol values, and risk reduction in primary prevention statin trials

HS Hecht - Current atherosclerosis reports, 2011 - Springer
The emergence of atherosclerosis imaging, using coronary calcium scanning (CAC) and
carotid intima media thickness (CIMT) and plaque as stronger predictors of cardiovascular …

Subclinical atherosclerosis as a target of therapy: potential role of statins

JJP Kastelein, ESG Stroes, E de Groot - American Journal of …, 2004 - ajconline.org
Cardiovascular events are preceded by the asymptomatic development of atherosclerosis
over many decades. Early atherosclerotic lesions have been described even in the womb, 1 …

Cardiovascular disease risk assessment: review of established and newer modalities

DM Tehrani, ND Wong - Current treatment options in cardiovascular …, 2015 - Springer
Opinion statement Cardiovascular disease (CVD) risk assessment has changed
substantially in recent years. Statins are recommended for a larger proportion of Americans …

[HTML][HTML] Prevalence and significance of risk enhancing biomarkers in the United States population at intermediate risk for atherosclerotic disease

GL Vega, J Wang, SM Grundy - Journal of Clinical Lipidology, 2022 - Elsevier
Background Pooled cohort equations (PCEs) estimate 10-year risk for atherosclerotic
cardiovascular disease (ASCVD) in US adults. One use is to guide statin eligibility. However …

[HTML][HTML] Role of cardiovascular imaging in risk assessment: recent advances, gaps in evidence, and future directions

F Perone, M Bernardi, A Redheuil, D Mafrica… - Journal of Clinical …, 2023 - mdpi.com
Optimal risk assessment for primary prevention remains highly challenging. Recent
registries have highlighted major discrepancies between guidelines and daily practice …

Strategies for treating lipids for prevention: risk stratification models with and without imaging

TM Okwuosa, S Mallikethi-Reddy… - Best Practice & Research …, 2014 - Elsevier
Cardiovascular disease (CVD) remains the leading cause of mortality both in the United
States and worldwide. Traditional risk factors are essential to CVD risk prediction and …