Question I have several patients with autism spectrum disorder (ASD) who experience
difficulties with sleep, affecting the quality of life of both the child and the family. Is melatonin …

Dear Editor, In a recent article of this journal, Wright et al.(2010) reported results of the
largest randomized controlled trial to date of oral melatonin for disordered sleep in …

Sleep disorders arise from a variety of causes and are thought to affect 20–30% of typically
developing (ie, nonspecial-needs) children. 1 This frequency increases to up to 80% in …

Melatonin is a hormone produced by the brain in response to low levels of light. It plays an
important role in the regulation of the internal circadian clock as well as sleep/wake …

Robust clinical evidence has not been available for melatonin, a drug commonly
administered for treating sleep problems of children with autism spectrum disorder (ASD). In …

Long-term effectiveness of controlled-release melatonin in 25 children, aged 2.6–9.6 years
with autism without other coexistent pathologies was evaluated openly. Sleep patterns were …

Supplemental melatonin has shown promise in treating sleep onset insomnia in children
with autism spectrum disorders (ASD). Twenty-four children, free of psychotropic …

Background: Melatonin may be used to treat sleep disorders in both children and adults with
intellectual disability. The evidence for its efficacy, potential adverse effects and drug …

We describe our experience in using melatonin to treat insomnia, a common sleep concern,
in children with autism spectrum disorders. One hundred seven children (2—18 years of …

Ask the Editor Page 1 Journal of Autism and Developmental Disorders, Vol. 28, No. 4, 1998 Ask
the Editor What is melatonin? Is it a useful treatment for sleep problems in antism? Melatonin …